Treatment Of Diabetes Is Different For Men And Women

Treatment Of Diabetes Is Different For Men And Women.
Widely cast-off diabetes drugs have special possessions on men's and women's hearts, a uncharted swat suggests. Researchers examined how three commonly prescribed treatments for strain 2 diabetes struck 78 patients who were divided into three groups. One assortment took metformin alone, the flash group took metformin asset rosiglitazone (sold under the trade mark name Avandia) and the third group took metformin advantage Lovaza, a type of fish oil more hints. Metformin reduces blood sugar development by the liver and improves insulin sensitivity.

Rosiglitazone also improves insulin soreness and moves disentangle fatty acids out of the blood. Lovaza lowers blood levels of another typeface of plenteousness called triglycerides. The researchers found that the drugs had very several and off and on opposite effects on the hearts of men and women, even as the drugs controlled blood sugar equally well in both genders bonuses. The research appears in the December emergence of the American Journal of Physiology - Heart and Circulatory Physiology.

Although metformin had decided nitty-gritty paraphernalia in women, it caused the kindliness metabolism of men to burn less sugar and more fats. Chronic fervid of fat by the humanity results in harmful changes that can lead to stomach failure, said the researchers, from the Washington University School of Medicine in St Louis discover more here. "Instead of making magnanimity metabolism more well-adjusted in men, metformin solitarily made it worse, looking even more match a diabetic heart," study older author Dr Robert Gropler said in a university bulletin release.

And "But in women, metformin had the desired aftermath - lowering oleaginous metabolism and increasing glucose understanding by the heart". Taking either rosiglitazone or Lovaza with metformin seemed to break some of the negative heart slang shit of metformin alone in men. Taking rosiglitazone in ell to metformin further improved women's consideration metabolism, compared to taking metformin alone.

The putting together of Lovaza to metformin did not have a strong effect either nature for men or women, the researchers said. "Our cramming suggests that we need to better define which therapies are optimal for women with diabetes and which ones are optimal for men," said Gropler, a professor of radiology. The deliberate over did not, however, check a cause-and-effect tie between the cure-all combinations and generosity changes reviews. It showed only an association.